For research use only. Not for therapeutic Use.
SC-560 (CAT: I012046) is a selective inhibitor of cyclooxygenase-1 (COX-1). Cyclooxygenases are enzymes responsible for the synthesis of prostanoids, including prostaglandins. SC-560 specifically targets and inhibits the activity of COX-1, which is involved in physiological processes such as maintaining gastric mucosal integrity and regulating platelet aggregation. This selective inhibition of COX-1 by SC-560 makes it a valuable tool for studying the role of COX-1 in various biological processes and investigating the potential therapeutic applications of COX-1 inhibition.
| Catalog Number | I012046 |
| CAS Number | 188817-13-2 |
| Synonyms | SC 560; 5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole |
| Molecular Formula | C17H12ClF3N2O |
| Purity | ≥95% |
| Target | COX |
| Solubility | Soluble in DMSO > 10 mM |
| Storage | Store at +4°C |
| IUPAC Name | 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)pyrazole |
| InChI | InChI=1S/C17H12ClF3N2O/c1-24-14-8-6-13(7-9-14)23-15(10-16(22-23)17(19,20)21)11-2-4-12(18)5-3-11/h2-10H,1H3 |
| InChIKey | PQUGCKBLVKJMNT-UHFFFAOYSA-N |
| SMILES | COc1ccc(cc1)n1nc(cc1c1ccc(Cl)cc1)C(F)(F)F |
