SCH 529074

• CAT Number: I010923
• CAS Number: 922150-11-6
• Molecular Formula: C31H36Cl2N6
• Molecular Weight: 563.57
• Purity: ≥95%
• Synonyms: N3-[2-[[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]methyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine
• Target: MDM-2/p53
• Solubility: Soluble to 100 mM in ethanol and to 10 mM in DMSO with sonication
• Storage: Store at -20°C
• IUPAC Name: N-[2-[[4-[bis(4-chlorophenyl)methyl]piperazin-1-yl]methyl]quinazolin-4-yl]-N/',N/'-dimethylpropane-1,3-diamine
• InChI: InChI=1S/C31H36Cl2N6/c1-37(2)17-5-16-34-31-27-6-3-4-7-28(27)35-29(36-31)22-38-18-20-39(21-19-38)30(23-8-12-25(32)13-9-23)24-10-14-26(33)15-11-24/h3-4,6-15,30H,5,16-22H2,1-2H3,(H,34,35,36)
• InChIKey: NCAJLQDPTZBGJV-UHFFFAOYSA-N
• SMILES: CN(C)CCCNC1=NC(=NC2=CC=CC=C21)CN3CCN(CC3)C(C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

SCH 529074（Cat No.:I010923） is a selective agonist of the dopamine D4 receptor with an EC50 value of 39 nM. It has a high affinity for D4 receptors and a low affinity for other dopamine receptors, as well as a negligible affinity for other receptors. SCH 529074 has been shown to have anxiolytic and antipsychotic effects in preclinical studies and is being investigated for potential therapeutic use in the treatment of various psychiatric disorders.