Scillarenin

• CAT Number: R054369
• CAS Number: 465-22-5
• Molecular Formula: C24H32O4
• Molecular Weight: 384.516
• Purity: ≥95%
• Synonyms: (3β)-3,14-Dihydroxybufa-4,20,22-trienolide; 3β,14-Dihydroxybufa-4,20,22-trienolide; 3β-Scillarenin; Cardiogenin; NSC 234669; Scillarenin A; Scillarenine; β-Scillarenin
• Storage: Store at RT
• IUPAC Name: 5-[(3S,8R,9S,10R,13R,14S,17R)-3,14-dihydroxy-10,13-dimethyl-1,2,3,6,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pyran-2-one
• InChI: InChI=1S/C24H32O4/c1-22-10-7-17(25)13-16(22)4-5-20-19(22)8-11-23(2)18(9-12-24(20,23)27)15-3-6-21(26)28-14-15/h3,6,13-14,17-20,25,27H,4-5,7-12H2,1-2H3/t17-,18+,19-,20+,22-,23+,24-/m0/s1
• InChIKey: OVUOVMIMOCJILI-KFZANIOBSA-N
• SMILES: CC12CCC(C=C1CCC3C2CCC4(C3(CCC4C5=COC(=O)C=C5)O)C)O

Scillarenin is a bioactive cardiac glycoside found in the bulbs of the plant species Urginea maritima, commonly known as squill. It has potent effects on the heart, increasing the force of cardiac contractions and used traditionally to treat heart failure and arrhythmias. Scillarenin acts by inhibiting the sodium-potassium ATPase enzyme, leading to increased intracellular calcium concentrations. This compound is studied for its potential therapeutic applications and its role in enhancing cardiac function and treating heart-related conditions.