For research use only. Not for therapeutic Use.
Scoparone is a constituent of the Chinese herb <em>Artemisia</em> and has been identified as having anticoagulant, hypolipidemic, vasorelaxant, antioxidant, and anti-<wbr></wbr>inflammatory actions in experimental models. It has been investigated for its bilirubin enhancing effect in up-regulating bilirubin excretion enzymes, such as sulfotransferase or UDP-glucuronosyl<wbr></wbr>transferase 1A1. It has also been shown to suppress nitric oxide, prostaglandin E2 (Item No. <span class=/itemid/>14010</span>), and inflammatory cytokine production, as well as to attenuate IgE-mediated allergic response in mast cells and to inhibit passive cutaneous anaphylaxis in rats.
| Catalog Number | R063663 |
| CAS Number | 120-08-1 |
| Synonyms | 6,7-Dimethoxy-2H-chromen-2-one; 6,7-Dimethoxycoumarin; 6,7-Dimethylesculetin; Aesculetin Dimethyl Ether; Escoparone; Esculetin 6,7-Dimethyl Ether; Esculetin Dimethyl Ether; NRB 03190; O,O-Dimethylesculetin; O-Methylisoscopoletin; O-Methylscopoletin; |
| Molecular Formula | C11H10O4 |
| Purity | ≥95% |
| Target | Disease Research Fields |
| Storage | -20°C |
| IUPAC Name | 6,7-dimethoxychromen-2-one |
| InChI | InChI=1S/C11H10O4/c1-13-9-5-7-3-4-11(12)15-8(7)6-10(9)14-2/h3-6H,1-2H3 |
| InChIKey | GUAFOGOEJLSQBT-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)C=CC(=O)O2)OC |
