For research use only. Not for therapeutic Use.
SCR-1481B1 (Metatinib anhydrous) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor.
More details please refer to Patent WO 2009094417 A1.
| Catalog Number | I009417 |
| CAS Number | 1174161-86-4 |
| Synonyms | [3-[[4-(2-amino-3-chloropyridin-4-yl)oxy-3-fluorophenyl]carbamoyl]-5-(4-fluorophenyl)-4-oxopyridin-1-yl]methyl dihydrogen phosphate;2-amino-2-(hydroxymethyl)propane-1,3-diol |
| Molecular Formula | C32H40ClF2N6O13P |
| Purity | ≥95% |
| InChI | InChI=1S/C24H18ClF2N4O7P.C4H11NO3/c25-21-20(7-8-29-23(21)28)38-19-6-5-15(9-18(19)27)30-24(33)17-11-31(12-37-39(34,35)36)10-16(22(17)32)13-1-3-14(26)4-2-13;5-4(1-6,2-7)3-8/h1-11H,12H2,(H2,28,29)(H,30,33)(H2,34,35,36);6-8H,1-3,5H2 |
| InChIKey | SDCKZXWUASKHNF-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C2=CN(C=C(C2=O)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F)COP(=O)(O)O)F.C(C(CO)(CO)N)O |
| Reference | [1]. Robert M. Borzilleri, et al. 4-pyridinone compounds and their use for cancer. WO/2009094417/A1. |
