For research use only. Not for therapeutic Use.
SMDA (Cat No.: I013713) is a methylated form of the amino acid arginine. It is naturally present in all nucleated cells and can be released into the circulatory system through proteolysis. Once in circulation, SMDA is primarily excreted by the kidneys. If you need to, please contact us in time, and we will reply to you as soon as possible within 24 hours.
| Catalog Number | I013713 |
| CAS Number | 30344-00-4 |
| Molecular Formula | C₈H₁₈N₄O₂ |
| Purity | ≥95% |
| Target | Endogenous Metabolite |
| Solubility | DMSO: 8.33 mg/mL |
| Storage | Room temperature |
| IUPAC Name | (2S)-2-amino-5-[(N,N//'-dimethylcarbamimidoyl)amino]pentanoic acid |
| InChI | InChI=1S/C8H18N4O2/c1-10-8(11-2)12-5-3-4-6(9)7(13)14/h6H,3-5,9H2,1-2H3,(H,13,14)(H2,10,11,12)/t6-/m0/s1 |
| InChIKey | HVPFXCBJHIIJGS-LURJTMIESA-N |
| SMILES | CNC(=NC)NCCCC(C(=O)O)N |
| Reference | [1]. Bode-Böger SM,et al. Symmetrical dimethylarginine: a new combined parameter for renal function and extent ofcoronary artery disease.<br>[2]. Schepers E, et al. Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease.Clin J Am Soc Nephrol. 2011 Oct;6(10):2374-83. <br>[3]. Nabity MB, et al. Symmetric Dimethylarginine Assay Validation, Stability, and Evaluation as a Marker for the EarlyDetection of Chronic Kidney Disease in Dogs. J Vet Intern Med. 2015 Jul-Aug;29(4):1036-44. <br>[4]. Veldink H, et al. Effects of chronic SDMA infusion on glomerular filtration rate, blood pressure, myocardial function and renal histology in C57BL6/J mice. Nephrol Dial Transplant. 2013 Jun;28(6):1434-9. |
