For research use only. Not for therapeutic Use.
SDZ 220-040(CAT: M040982) is a competitive antagonist of the mammalian NMDA (N-methyl-D-aspartate) receptor, a key receptor in the central nervous system involved in excitatory neurotransmission, synaptic plasticity, learning, and memory. By competitively inhibiting the glutamate binding site on the NMDA receptor, SDZ 220-040 reduces calcium influx and neuronal excitability, making it a valuable tool for studying excitotoxicity, neurodegeneration, and seizure mechanisms. It is widely used in neuroscience research to explore NMDA receptor function and to evaluate potential therapeutic strategies for conditions such as stroke, epilepsy, and Alzheimer’s disease.
| CAS Number | 174575-40-7 |
| Synonyms | (2S)-2-amino-3-[5-(2,4-dichlorophenyl)-2-hydroxy-3-(phosphonomethyl)phenyl]propanoic acid |
| Molecular Formula | C16H16Cl2NO6P |
| Purity | ≥95% |
| IUPAC Name | (2S)-2-amino-3-[5-(2,4-dichlorophenyl)-2-hydroxy-3-(phosphonomethyl)phenyl]propanoic acid |
| InChI | InChI=1S/C16H16Cl2NO6P/c17-11-1-2-12(13(18)6-11)8-3-9(5-14(19)16(21)22)15(20)10(4-8)7-26(23,24)25/h1-4,6,14,20H,5,7,19H2,(H,21,22)(H2,23,24,25)/t14-/m0/s1 |
| InChIKey | NYZFUZCCDOSQBG-AWEZNQCLSA-N |
| SMILES | C1=CC(=C(C=C1Cl)Cl)C2=CC(=C(C(=C2)CP(=O)(O)O)O)CC(C(=O)O)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
