SDZ 220-581 hydrochloride

For research use only. Not for therapeutic Use.

  • CAT Number: I002324
  • CAS Number: 179411-93-9
  • Molecular Formula: C16H18Cl2NO5P
  • Molecular Weight: 406.2
  • Purity: ≥95%
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SDZ 220-581 hydrochloride (Cat.No:I002324) is a chemical compound that acts as a selective antagonist of the N-methyl-D-aspartate (NMDA) receptor. It has been studied for its potential neuroprotective effects in various neurological conditions, including stroke and neurodegenerative diseases. Further research is ongoing to explore its therapeutic applications and safety profile.


Catalog Number I002324
CAS Number 179411-93-9
Synonyms

(S)-2-amino-3-(2/’-chloro-5-(phosphonomethyl)-[1,1/’-biphenyl]-3-yl)propanoic acid hydrochloride

Molecular Formula C16H18Cl2NO5P
Purity ≥95%
Target Neuronal Signaling
Solubility DMSO: ≤ 5 mg/mL
Storage Store at -20C
Reference

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<br>[1]. Gilmour G, et al. In vitro characterisation of the novel positive allosteric modulators of the mGlu? receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat. Neuropharmacology. 2013 Jan;64:224-39.
<br>[2]. Linderholm K, et al. Role of the NMDA-receptor in Prepulse Inhibition in the Rat. Int J Tryptophan Res. 2010;3:1-12.
<br>[3]. Urwyler S, et al. Biphenyl-derivatives of 2-amino-7-phosphono-heptanoic acid, a novel class of potent competitive N-methyl-D-aspartate receptor antagonists–II. Pharmacological characterization in vivo. Neuropharmacology. 1996 Jun;35(6):655-69.
<br>[4]. Bakshi VP, et al. Disruption of prepulse inhibition and increases in locomotor activity by competitive N-methyl-D-aspartate receptor antagonists in rats. J Pharmacol Exp Ther. 1999 Feb;288(2):643-52.
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