For research use only. Not for therapeutic Use.
Potent, selective and orally active A1 adenosine receptor agonist.
KEYWORDS: SDZ-WAG 994 | supplier | A1 agonist | WAG 994 | N-Cyclohexyl-2′-O-methyladenosine | SDZ-WAG994 | WAG994 | WAG-994 | CAS [130714-47-5] | Adenosine | A1 | Agonist | Receptors
| Catalog Number | M113038 |
| CAS Number | 130714-47-5 |
| Molecular Formula | C17H25N5O4 |
| Purity | ≥95% |
| IUPAC Name | (2R,3R,4R,5R)-5-[6-(cyclohexylamino)purin-9-yl]-2-(hydroxymethyl)-4-methoxyoxolan-3-ol |
| InChI | InChI=1S/C17H25N5O4/c1-25-14-13(24)11(7-23)26-17(14)22-9-20-12-15(18-8-19-16(12)22)21-10-5-3-2-4-6-10/h8-11,13-14,17,23-24H,2-7H2,1H3,(H,18,19,21)/t11-,13-,14-,17-/m1/s1 |
| SMILES | CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC4CCCCC4)CO)O |
| Reference | RA Seymour et al. The efficacy of a novel adenosine agonist (WAG 994) in postoperative dental pain. Br. J. Clin. Pharmacol. 1999, 47(6), 675–680.
Wagner et al. General pharmacology of SDZ WAG 994, a potent selective and orally active adenosine A1 receptor agonist. Drug Dev. Res. 1995, 34, 276.
Bertolet B.D. et al. Circulation. Effects of A1 adenosine receptor agonism using N6-cyclohexyl-2′-O-methyladenosine in patients with left ventricular dysfunction. 1996, 94, 1212-1215. |
