For research use only. Not for therapeutic Use.
SecinH3(Cat No.:I010278) is a selective inhibitor of cytosines, a family of guanine nucleotide exchange factors (GEFs) involved in cellular signaling pathways. It exhibits inhibitory activity with IC50 values of 2.4 μM for hCyh2, 5.4 μM for hCyh1 and mCyh3, and 5.6 μM for hCyh3 and drosophila steppe. However, it shows lower potency with an IC50 of 65 μM for yGea2-S7. The selective inhibition of cytosine by SecinH3 makes it a valuable tool for studying the functions of cytosines and their associated signaling processes in various biological contexts.
Catalog Number | I010278 |
CAS Number | 853625-60-2 |
Synonyms | N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide |
Molecular Formula | C24H20N4O4S |
Purity | ≥95% |
Target | Apoptosis |
Solubility | Soluble to 100 mM in DMSO and to 10 mM in ethanol with gentle warming |
Storage | Store at +4C |
InChIKey | QELIXRUQGQOCBE-UHFFFAOYSA-N |