seco-(8,9)-Buspirone Carboxylic Acid

• CAT Number: C001094
• CAS Number: 257877-43-3
• Molecular Formula: C₂₁H₃₃N₅O₃
• Molecular Weight: 403.52
• Purity: ≥95%
• Synonyms: 1-[2-oxo-2-[[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]amino]ethyl]-cyclopentaneacetic Acid; 1-[2-oxo-2-[[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]amino]ethyl]-cyclopentaneacetic Acid
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Appearance: White to Off-White Solid
• Storage: 4°C
• IUPAC Name: 2-[1-[2-oxo-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butylamino]ethyl]cyclopentyl]acetic acid
• InChI: InChI=1S/C21H33N5O3/c27-18(16-21(17-19(28)29)6-1-2-7-21)22-8-3-4-11-25-12-14-26(15-13-25)20-23-9-5-10-24-20/h5,9-10H,1-4,6-8,11-17H2,(H,22,27)(H,28,29)
• InChIKey: CXFNXCYJILJTDA-UHFFFAOYSA-N
• SMILES: C1CCC(C1)(CC(=O)NCCCCN2CCN(CC2)C3=NC=CC=N3)CC(=O)O

Seco-(8,9)-Buspirone Carboxylic Acid (Cat No.:C001094) is a chemical compound that is a derivative of buspirone, a drug used to treat anxiety disorders. The term “seco” indicates that a part of the original buspirone molecule has been cleaved, resulting in the formation of a carboxylic acid derivative. This modification may affect the pharmacological properties of buspirone. Seco-(8,9)-Buspirone Carboxylic Acid is of interest in pharmaceutical research to investigate the metabolism and potential interactions of buspirone derivatives.

Reference

Wu, Y.H., et al.: J. Med. Chem., 15, 477 (1972); Allen, L.E., et al.: Arzneim.-Forsch., 24, 917 (1974); Goa, K.L., et al.: Drugs, 32, 114 (1986);