Selepressin

• CAT Number: I009426
• CAS Number: 876296-47-8
• Molecular Formula: C46H73N13O11S2
• Molecular Weight: 1048.29
• Purity: ≥95%
• Synonyms: Selepressin; FE 202158; FE202158; FE-202158. [Phe(2),Ile(3), Hgn(4),Orn(iPr)(8)]vasopressin;(S)-N-((S)-1-((2-amino-2-oxoethyl)amino)-5-(isopropylamino)-1-oxopentan-2-yl)-1-((4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(4-amino-4-oxobuty
• Target: Vasopressin Receptor
• Solubility: Soluble in DMSO
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: (2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-10-(4-amino-4-oxobutyl)-7-(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-5-(propan-2-ylamino)pentan-2-yl]pyrrolidine-2-carboxamide
• InChI: InChI=1S/C46H73N13O11S2/c1-5-26(4)38-45(69)54-30(14-9-17-35(48)60)41(65)56-32(21-36(49)61)42(66)57-33(24-72-71-23-28(47)39(63)55-31(43(67)58-38)20-27-12-7-6-8-13-27)46(70)59-19-11-16-34(59)44(68)53-29(15-10-18-51-25(2)3)40(64)52-22-37(50)62/h6-8,12-13,25-26,28-34,38,51H,5,9-11,14-24,47H2,1-4H3,(H2,48,60)(H2,49,61)(H2,50,62)(H,52,64)(H,53,68)(H,54,69)(H,55,63)(H,56,65)(H,57,66)(H,58,67)/t26-,28-,29-,30-,31-,32-,33-,34-,38-/m0/s1
• InChIKey: JCVQBJTWWDYUFQ-MRUTUVJXSA-N
• SMILES: CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N1)CC2=CC=CC=C2)N)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCCNC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCCC(=O)N

Selepressin(CAT: I009426) is a synthetic, selective vasopressin V1a receptor agonist designed for use in conditions such as septic shock. By specifically targeting V1a receptors, it promotes vasoconstriction without significant effects on V2 receptors, reducing the risk of fluid overload commonly associated with non-selective vasopressin analogs. This compound is particularly valuable in critical care and cardiovascular research, aiding studies on vasopressor therapies and vascular tone regulation. Selepressin offers insights into improving outcomes in sepsis and other conditions requiring precise modulation of vascular resistance, making it a promising tool in the development of advanced treatments for shock and related disorders.