Semapimod HCl

For research use only. Not for therapeutic Use.

  • CAT Number: M002956
  • CAS Number: 164301-51-3
  • Molecular Formula: C34H56Cl4N18O2
  • Molecular Weight: 890.746
  • Purity: ≥95%
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Catalog Number M002956
CAS Number 164301-51-3
Synonyms

SeMapiMod (tetrahydrochloride);Semapimod hydrochloride

Molecular Formula C34H56Cl4N18O2
Purity ≥95%
Storage Store at -20°C
InChIKey MAHASPGBAIQZLY-RTQZJKMDSA-N
SMILES CC(=NN=C(N)N)C1=CC(=CC(=C1)NC(=O)CCCCCCCCC(=O)NC2=CC(=CC(=C2)C(=NN=C(N)N)C)C(=NN=C(N)N)C)C(=NN=C(N)N)C.Cl.Cl.Cl.Cl
Reference

1: Dotan I, Rachmilewitz D, Schreiber S, Eliakim R, van der Woude CJ, Kornbluth
A, Buchman AL, Bar-Meir S, Bokemeyer B, Goldin E, Maaser C, Mahadevan U, Seidler
U, Hoffman JC, Homoky D, Plasse T, Powers B, Rutgeerts P, Hommes D;
Semapimod-CD04/CD05 Investigators. A randomised placebo-controlled multicentre
trial of intravenous semapimod HCl for moderate to severe Crohn/’s disease. Gut.
2010 Jun;59(6):760-6. doi: 10.1136/gut.2009.179994. PubMed PMID: 20551461.

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2: Noelker C, Stuckenholz V, Reese JP, Alvarez-Fischer D, Sankowski R, Rausch T,
Oertel WH, Hartmann A, van Patten S, Al-Abed Y, Bacher M. CNI-1493 attenuates
neuroinflammation and dopaminergic neurodegeneration in the acute MPTP mouse
model of Parkinson/’s disease. Neurodegener Dis. 2013;12(2):103-10. doi:
10.1159/000342714. Epub 2012 Nov 7. PubMed PMID: 23147695.

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