Senktide

• CAT Number: I013023
• CAS Number: 106128-89-6
• Molecular Formula: C₄₀H₅₅N₇O₁₁S
• Molecular Weight: 841.97
• Purity: ≥95%
• Target: Neuronal Signaling
• Solubility: DMSO
• IUPAC Name: (3S)-4-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(3-carboxypropanoylamino)-4-oxobutanoic acid
• InChI: InChI=1S/C40H55N7O11S/c1-24(2)19-28(37(55)45-27(36(41)54)17-18-59-4)44-33(49)23-42-39(57)31(21-26-13-9-6-10-14-26)47(3)40(58)30(20-25-11-7-5-8-12-25)46-38(56)29(22-35(52)53)43-32(48)15-16-34(50)51/h5-14,24,27-31H,15-23H2,1-4H3,(H2,41,54)(H,42,57)(H,43,48)(H,44,49)(H,45,55)(H,46,56)(H,50,51)(H,52,53)/t27-,28-,29-,30-,31-/m0/s1
• InChIKey: HMHYXLVEFVGOPM-QKUYTOGTSA-N
• SMILES: CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)N(C)C(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(=O)O)NC(=O)CCC(=O)O

Senktide(CAT: I013023) is a potent and selective agonist of the neurokinin-3 (NK3) receptor, which plays a critical role in modulating neurotransmission and neuroendocrine functions. By activating NK3 receptors, Senktide is widely used in neuroscience research to study the mechanisms of tachykinin signaling and its involvement in conditions such as stress, pain, and neurodegenerative diseases. It is also valuable in investigating reproductive endocrinology, as NK3 receptors are involved in the regulation of gonadotropin-releasing hormone (GnRH) secretion. With its high specificity, Senktide provides researchers with a robust tool for exploring therapeutic targets within the tachykinin receptor family.