For research use only. Not for therapeutic Use.
Sennidin A (Cat No.:I016754) is a natural compound derived from the Senna plant, commonly known as Cassia Angustifolia. It belongs to a class of compounds called anthraquinones and is known for its laxative properties. Sennidin A acts by stimulating bowel movements and promoting intestinal contractions, which helps alleviate constipation. It is often used in the formulation of herbal laxatives and over-the-counter products for relieving occasional or short-term constipation. Sennidin A’s mechanism of action involves increasing water content in the intestines, softening stool consistency, and facilitating its passage through the digestive system.
| CAS Number | 641-12-3 |
| Molecular Formula | C₃₀H₁₈O₁₀ |
| Purity | ≥95% |
| Target | PI3K/Akt/mTOR |
| IUPAC Name | 9-(2-carboxy-4,5-dihydroxy-10-oxo-9H-anthracen-9-yl)-4,5-dihydroxy-10-oxo-9H-anthracene-2-carboxylic acid |
| InChI | InChI=1S/C30H18O10/c31-17-5-1-3-13-21(15-7-11(29(37)38)9-19(33)25(15)27(35)23(13)17)22-14-4-2-6-18(32)24(14)28(36)26-16(22)8-12(30(39)40)10-20(26)34/h1-10,21-22,31-34H,(H,37,38)(H,39,40) |
| InChIKey | JPMRHWLJLNKRTJ-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C(=C1)O)C(=O)C3=C(C2C4C5=C(C(=CC=C5)O)C(=O)C6=C4C=C(C=C6O)C(=O)O)C=C(C=C3O)C(=O)O |
| Reference | [1]. Furuta A, et al. Identification of Hydroxyanthraquinones as Novel Inhibitors of Hepatitis C Virus NS3 Helicase. Int J Mol Sci. 2015 Aug 7;16(8):18439-53.<br>[2]. Daigo Abe, et al. Sennidin stimulates glucose incorporation in rat adipocytes. Life Sciences. 2006. |
