Sennoside A

• CAT Number: R062585
• CAS Number: 81-27-6
• Molecular Formula: C42H38O20
• Molecular Weight: 862.746
• Purity: ≥95%
• Synonyms: (R*,R*)-5,5’-Bis(β-D-glucopyranosyloxy)-9,9’,10,10’-tetrahydro-4,4’-dihydroxy-10,10’-dioxo[9,9’-Bianthracene]-2,2’-dicarboxylic Acid; Gentle Nature; Glysennid; NSC 112929
• Target: MAO
• Storage: 3 years -20C powder
• IUPAC Name: (9R)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
• InChI: InChI=1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26-,31-,32-,35+,36+,37-,38-,41-,42-/m1/s1
• InChIKey: IPQVTOJGNYVQEO-KGFNBKMBSA-N
• SMILES: C1=CC2=C(C(=C1)OC3C(C(C(C(O3)CO)O)O)O)C(=O)C4=C(C2C5C6=C(C(=CC=C6)OC7C(C(C(C(O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O

Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine through regulating the spontaneous motility of colon.LD50: Mice 5000 mg/kg (i.g.); Rats 5000mg/kg (i.g.).