Serine Hydrolase inhibitor-21

• CAT Number: I041159
• CAS Number: 366448-34-2
• Molecular Formula: C18H12N2O2S
• Molecular Weight: 320.37
• Purity: ≥95%
• Synonyms: 5-(phenothiazine-10-carbonyl)-1H-pyridin-2-one
• InChI: InChI=1S/C18H12N2O2S/c21-17-10-9-12(11-19-17)18(22)20-13-5-1-3-7-15(13)23-16-8-4-2-6-14(16)20/h1-11H,(H,19,21)
• InChIKey: FRWOZZSGXZOOSM-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)N(C3=CC=CC=C3S2)C(=O)C4=CNC(=O)C=C4

Serine Hydrolase inhibitor-21 (compound 8), a pyridine, is a serine hydrolase inhibitor with a Ki of 429 nM for BuChE. Serine Hydrolase inhibitor-21 has the potential for Alzheimer’s disease research[1].

Reference

[1]. Sultan Darvesh, et al. Novel pyridones and their use as modulators of serine hydrolase enzymes. WO2001077078A1.