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85650-57-3-Setiptiline maleate Setiptiline maleate

Setiptiline maleate

For research use only. Not for therapeutic Use.

  • CAT Number: I005139
  • CAS Number: 85650-57-3
  • Molecular Formula: C23H23NO4
  • Molecular Weight: 377.43
  • Purity: ≥95%
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Related Small Molecules: CD38 Protein, Human (HEK293, C-His)     Estriol succinate     GW779439X    

<p style=/line-height:25px/>Setiptiline is a serotonin receptor antagonist.<br>IC50 value:<br>Target: 5-HT receptor<br>Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine. From Wikipedia.</p>


Catalog Number I005139
CAS Number 85650-57-3
Synonyms

2-methyl-2,3,4,9-tetrahydro-1H-dibenzo[3,4:6,7]cyclohepta[1,2-c]pyridine maleate

Molecular Formula C23H23NO4
Purity ≥95%
Target Neuronal Signaling
Solubility 10 mM in DMSO
Storage Store at -20°C
Reference

<p style=/line-height:25px/>
<br>[1]. Yamada K, Furukawa T. [Behavioral effects of a new antidepressant, setiptiline]. Nihon Yakurigaku Zasshi. 1991 Jan;97(1):31-9.
Abstract

<br>[2]. Kamimura M, Aoba A, Yamaguchi N et al. The effect of age on plasma level of setiptiline maleate in depressed patients. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Oct;18(6):1015-26.

<br>[3]. Kuniyoshi M, Nakamura J, Miura C, Inanaga K. Effectiveness of concomitant setiptiline maleate (Tecipul) on negative symptoms of schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Mar;18(2):339-46.

<br>[4]. Niho T, Ito C, Shibutani Y, Hashizume H, Yamaguchi K. [Pharmacological properties of MO-8282, a novel antidepressant]. Nihon Yakurigaku Zasshi. 1986 Oct;88(4):309-20.

<br>[5]. Setiptiline

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