Sevelamer HCl

• CAT Number: A000462
• CAS Number: 152751-57-0
• Molecular Formula: C6H13Cl2NO
• Molecular Weight: 186.08
• Purity: ≥95%
• Storage: 3 years -20C powder
• IUPAC Name: 2-(chloromethyl)oxirane;prop-2-en-1-amine;hydrochloride
• InChI: InChI=1S/C3H5ClO.C3H7N.ClH/c4-1-3-2-5-3;1-2-3-4;/h3H,1-2H2;2H,1,3-4H2;1H
• InChIKey: KHNXRSIBRKBJDI-UHFFFAOYSA-N
• SMILES: C=CCN.C1C(O1)CCl.Cl

Sevelamer HCl（Cat No.:A000462）is a phosphate binder commonly used to manage hyperphosphatemia in patients with chronic kidney disease (CKD), especially those on dialysis. By binding to dietary phosphate in the gastrointestinal tract, Sevelamer HCl prevents phosphate absorption, effectively lowering serum phosphate levels. Unlike calcium-based binders, Sevelamer HCl does not contribute to calcium overload, reducing the risk of vascular calcification. Additionally, it may have beneficial effects on lipid profiles by lowering LDL cholesterol. Sevelamer HCl is essential for improving phosphate management and enhancing cardiovascular health in CKD patients.