For research use only. Not for therapeutic Use.
SF 11 is a (Cat.No:I010847) NPY Y<sub>2</sub> antagonist (IC<sub>50</sub> = 199 nM). Displays no affinity for Y<sub>1</sub> receptor at concentrations up to 35 <span class=/’symbol/’>μ</span>M. Causes significant lethality in mice. Brain penetrant.
| Catalog Number | I010847 |
| CAS Number | 443292-81-7 |
| Synonyms | N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide |
| Molecular Formula | C27H30N2O2S |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| Storage | Store at +4C |
| IUPAC Name | N-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]piperidine-1-carbothioamide |
| InChI | InChI=1S/C27H30N2O2S/c1-2-31-25-15-13-24(14-16-25)28-26(32)29-19-17-23(18-20-29)27(30,21-9-5-3-6-10-21)22-11-7-4-8-12-22/h3-16,23,30H,2,17-20H2,1H3,(H,28,32) |
| InChIKey | PMEQBGAGFZDWQX-UHFFFAOYSA-N |
| SMILES | CCOC1=CC=C(C=C1)NC(=S)N2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O |
