For research use only. Not for therapeutic Use.
SGC2085(CAT: I002365) is a potent and selective inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1), a key enzyme involved in epigenetic regulation and transcriptional activation. By specifically targeting CARM1, it blocks the methylation of arginine residues on histones and transcriptional coactivators, disrupting processes critical for gene expression. This compound is particularly valuable in epigenetics research, aiding studies into the role of CARM1 in cancer, inflammation, and metabolic diseases. SGC2085 serves as a powerful tool for elucidating the biological functions of CARM1 and developing therapeutic strategies targeting epigenetic modulation.
| Catalog Number | I002365 |
| CAS Number | 1821908-48-8 |
| Molecular Formula | C19H24N2O2 |
| Purity | ≥95% |
| Target | Histone Methyltransferase |
| Solubility | DMSO：≥ 32 mg/mL |
| Storage | Store at -20°C |
| IUPAC Name | (2S)-2-amino-N-[[4-(3,5-dimethylphenoxy)-3-methylphenyl]methyl]propanamide |
| InChI | InChI=1S/C19H24N2O2/c1-12-7-13(2)9-17(8-12)23-18-6-5-16(10-14(18)3)11-21-19(22)15(4)20/h5-10,15H,11,20H2,1-4H3,(H,21,22)/t15-/m0/s1 |
| InChIKey | GLFOFXKMALJTCZ-HNNXBMFYSA-N |
| SMILES | CC1=CC(=CC(=C1)OC2=C(C=C(C=C2)CNC(=O)[C@H](C)N)C)C |
