SGD-1910

For research use only. Not for therapeutic Use.

  • CAT Number: I016697
  • CAS Number: 1342820-51-2
  • Molecular Formula: C₆₀H₆₄N₈O₁₂
  • Molecular Weight: 1089.2
  • Purity: ≥95%
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SGD-1910 (Cat.No:I016697) is a drug-linker conjugate for ADC by using the antitumor antibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via the cleavable linker MC-Val-Ala.


Catalog Number I016697
CAS Number 1342820-51-2
Molecular Formula C₆₀H₆₄N₈O₁₂
Purity ≥95%
Target Drug-Linker Conjugates for ADC
Reference

[1]. John A Hartley. Antibody-drug conjugates (ADCs) delivering pyrrolobenzodiazepine (PBD) dimers for cancer therapy. Expert Opin Biol Ther. 2020 Jun 16;1-13. <br>[2]. Jeffrey SC, et al. A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology. Bioconjug Chem. 2013 Jul 17;24(7):1256-63.

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