For research use only. Not for therapeutic Use.
SGD-1910 (Cat.No:I016697) is a drug-linker conjugate for ADC by using the antitumor antibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via the cleavable linker MC-Val-Ala.
| Catalog Number | I016697 |
| CAS Number | 1342820-51-2 |
| Molecular Formula | C₆₀H₆₄N₈O₁₂ |
| Purity | ≥95% |
| Reference | [1]. John A Hartley. Antibody-drug conjugates (ADCs) delivering pyrrolobenzodiazepine (PBD) dimers for cancer therapy. Expert Opin Biol Ther. 2020 Jun 16;1-13. <br>[2]. Jeffrey SC, et al. A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology. Bioconjug Chem. 2013 Jul 17;24(7):1256-63. |
