SH-4-54

• CAT Number: I001762
• CAS Number: 1456632-40-8
• Molecular Formula: C29H27F5N2O5S
• Molecular Weight: 610.59
• Purity: ≥95%
• Target: Stem Cell/Wnt
• Solubility: 10 mM in DMSO
• Storage: room temp
• IC50: 300 nM (KD, for STAT3)
• IUPAC Name: 4-[(4-cyclohexylphenyl)methyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]benzoic acid
• InChI: InChI=1S/C29H27F5N2O5S/c1-35(42(40,41)28-26(33)24(31)23(30)25(32)27(28)34)16-22(37)36(21-13-11-20(12-14-21)29(38)39)15-17-7-9-19(10-8-17)18-5-3-2-4-6-18/h7-14,18H,2-6,15-16H2,1H3,(H,38,39)
• InChIKey: VFPYGNNOSJWBHF-UHFFFAOYSA-N
• SMILES: CN(CC(=O)N(CC1=CC=C(C=C1)C2CCCCC2)C3=CC=C(C=C3)C(=O)O)S(=O)(=O)C4=C(C(=C(C(=C4F)F)F)F)F

SH-4-54（Cat No.:I001762）is a small molecule compound that acts as a selective antagonist of the dopamine D3 receptor. The D3 receptor is implicated in the regulation of mood, reward, and certain neuropsychiatric disorders, including addiction and schizophrenia. By blocking the D3 receptor, SH-4-54 may potentially reduce the reinforcing effects of substances like drugs and alcohol, making it a candidate for addiction therapies. Research is ongoing to assess its efficacy in treating conditions involving dopaminergic dysregulation, with particular focus on its safety, pharmacokinetics, and long-term therapeutic potential.