Shield-1

• CAT Number: I012228
• CAS Number: 914805-33-7
• Molecular Formula: C42H56N2O10
• Molecular Weight: 748.914
• Purity: ≥95%
• Synonyms: (1R)-3-(3,4-Dimethoxyphenyl)-1-[3-[2-(4-morpholinyl)ethoxy]phenyl]propyl (2S)-1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylate
• Target: Immunology/Inflammation
• IUPAC Name: [(1R)-3-(3,4-dimethoxyphenyl)-1-[3-(2-morpholin-4-ylethoxy)phenyl]propyl] (2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carboxylate
• InChI: InChI=1S/C42H56N2O10/c1-7-33(31-27-38(49-4)40(51-6)39(28-31)50-5)41(45)44-18-9-8-13-34(44)42(46)54-35(16-14-29-15-17-36(47-2)37(25-29)48-3)30-11-10-12-32(26-30)53-24-21-43-19-22-52-23-20-43/h10-12,15,17,25-28,33-35H,7-9,13-14,16,18-24H2,1-6H3/t33-,34-,35+/m0/s1
• InChIKey: NMFHJNAPXOMSRX-PUPDPRJKSA-N
• SMILES: CCC(C1=CC(=C(C(=C1)OC)OC)OC)C(=O)N2CCCCC2C(=O)OC(CCC3=CC(=C(C=C3)OC)OC)C4=CC(=CC=C4)OCCN5CCOCC5

Shield-1 (Cat.No:I012228) is a chemical compound widely used in research as a conditional protein stabilization tool. It interacts with a mutated FKBP domain (FKBP12*) to stabilize specific target proteins in cells. Shield-1’s ability to regulate protein stability has proven valuable in various biomedical and molecular biology studies, aiding researchers in elucidating protein functions.