For research use only. Not for therapeutic Use.
SIAIS164018 hydrochloride(CAT: I041007) is a small molecule inhibitor that targets a novel signaling pathway involved in the regulation of tumor cell survival and proliferation. By inhibiting the specific protein kinase X, SIAIS164018 hydrochloride disrupts critical pathways that enable cancer cells to evade apoptosis and continue uncontrolled growth. Preclinical studies have shown that SIAIS164018 hydrochloride is effective in a variety of solid tumors, including breast, lung, and pancreatic cancer. Its potential to synergize with other chemotherapeutic agents offers new avenues for combination therapies, providing a promising candidate for advanced cancer treatments and personalized oncology strategies.
| Catalog Number | I041007 |
| Synonyms | 4-[[2-[4-[1-[4-[[5-chloro-4-(2-dimethylphosphorylanilino)pyrimidin-2-yl]amino]-3-methoxyphenyl]piperidin-4-yl]piperazin-1-yl]-2-oxoethyl]amino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride |
| Molecular Formula | C43H49Cl2N10O7P |
| Purity | ≥95% |
| IUPAC Name | 4-[[2-[4-[1-[4-[[5-chloro-4-(2-dimethylphosphorylanilino)pyrimidin-2-yl]amino]-3-methoxyphenyl]piperidin-4-yl]piperazin-1-yl]-2-oxoethyl]amino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride |
| InChI | InChI=1S/C43H48ClN10O7P.ClH/c1-61-34-23-27(11-12-30(34)48-43-46-24-29(44)39(50-43)47-31-8-4-5-10-35(31)62(2,3)60)51-17-15-26(16-18-51)52-19-21-53(22-20-52)37(56)25-45-32-9-6-7-28-38(32)42(59)54(41(28)58)33-13-14-36(55)49-40(33)57;/h4-12,23-24,26,33,45H,13-22,25H2,1-3H3,(H,49,55,57)(H2,46,47,48,50);1H |
| InChIKey | CKXWIOLBMVQSCP-UHFFFAOYSA-N |
| SMILES | COC1=C(C=CC(=C1)N2CCC(CC2)N3CCN(CC3)C(=O)CNC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O)NC7=NC=C(C(=N7)NC8=CC=CC=C8P(=O)(C)C)Cl.Cl |
