For research use only. Not for therapeutic Use.
SID-852843 is a WNV NS2B-NS3 proteinase inhibitor. SID-852843 can inhibit WNV NS2B-NS3 proteinase activity with IC50 value of 0.105 μM. SID-852843 can be used for the research of virus infection[1].
SID-852843 can inhibit WNV NS2B-NS3 proteinase activity with IC50 value of 0.105 μM[1].
| Catalog Number | I012464 |
| CAS Number | 909859-19-4 |
| Synonyms | [5-amino-1-(4-methoxyphenyl)sulfonylpyrazol-3-yl] benzoate |
| Molecular Formula | C17H15N3O5S |
| Purity | ≥95% |
| InChI | InChI=1S/C17H15N3O5S/c1-24-13-7-9-14(10-8-13)26(22,23)20-15(18)11-16(19-20)25-17(21)12-5-3-2-4-6-12/h2-11H,18H2,1H3 |
| InChIKey | FQICFDBMQBCJDT-UHFFFAOYSA-N |
| SMILES | COC1=CC=C(C=C1)S(=O)(=O)N2C(=CC(=N2)OC(=O)C3=CC=CC=C3)N |
| Reference | [1]. Shyama Sidique, et al. Structure-activity relationship and improved hydrolytic stability of pyrazole derivatives that are allosteric inhibitors of West Nile Virus NS2B-NS3 proteinase. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5773-7. |
