For research use only. Not for therapeutic Use.
Sildenafil(Cat No.:A000031), commonly known by its brand name Viagra, is a medication primarily used to treat erectile dysfunction (ED) and pulmonary arterial hypertension. It works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5), which results in the dilation of blood vessels and increased blood flow, particularly in the genital area for ED treatment, and in the lungs for hypertension. Sildenafil helps maintain an erection but requires sexual stimulation to be effective. It has revolutionized the treatment of ED since its introduction in the late 1990s and remains a widely prescribed drug.
Catalog Number | A000031 |
CAS Number | 139755-83-2 |
Synonyms | Revatio, UK-92480, Viagra |
Molecular Formula | C22H30N6O4S |
Purity | ≥95% |
Target | PDE |
Solubility | >22.65mg/mL in DMSO |
Storage | Store at -20°C |
IUPAC Name | 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one |
InChI | InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29) |
InChIKey | BNRNXUUZRGQAQC-UHFFFAOYSA-N |
SMILES | CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C |