Sildenafil

For research use only. Not for therapeutic Use.

  • CAT Number: A000031
  • CAS Number: 139755-83-2
  • Molecular Formula: C22H30N6O4S
  • Molecular Weight: 474.60
  • Purity: ≥95%
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Sildenafil(Cat No.:A000031), commonly known by its brand name Viagra, is a medication primarily used to treat erectile dysfunction (ED) and pulmonary arterial hypertension. It works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5), which results in the dilation of blood vessels and increased blood flow, particularly in the genital area for ED treatment, and in the lungs for hypertension. Sildenafil helps maintain an erection but requires sexual stimulation to be effective. It has revolutionized the treatment of ED since its introduction in the late 1990s and remains a widely prescribed drug.


Catalog Number A000031
CAS Number 139755-83-2
Synonyms

Revatio, UK-92480, Viagra

Molecular Formula C22H30N6O4S
Purity ≥95%
Target PDE
Solubility >22.65mg/mL in DMSO
Storage Store at -20°C
IUPAC Name 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one
InChI InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)
InChIKey BNRNXUUZRGQAQC-UHFFFAOYSA-N
SMILES CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C

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