Sildenafil citrate

• CAT Number: A000759
• CAS Number: 171599-83-0
• Molecular Formula: C₂₂H₃₀N₆O₄S.C₆H₈O₇
• Molecular Weight: 666.71
• Purity: ≥95%
• Target: PDE
• Solubility: >25.4mg/mL in DMSO
• Storage: 3 years -20C powder
• IUPAC Name: 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one;2-hydroxypropane-1,2,3-tricarboxylic acid
• InChI: InChI=1S/C22H30N6O4S.C6H8O7/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28;7-3(8)1-6(13,5(11)12)2-4(9)10/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
• InChIKey: DEIYFTQMQPDXOT-UHFFFAOYSA-N
• SMILES: CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Sildenafil citrate（Cat No.:A000759）is a medication used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It works by inhibiting phosphodiesterase type 5 (PDE5), an enzyme that regulates blood flow in the penis. This inhibition enhances the effects of nitric oxide, leading to increased blood flow and an erection in response to sexual stimulation. For PAH, sildenafil relaxes blood vessels in the lungs, reducing blood pressure and improving exercise capacity. Common side effects include headaches, flushing, and dizziness. Sildenafil citrate is a widely recognized and effective treatment for ED and PAH.