Silibinin

• CAT Number: I002745
• CAS Number: 22888-70-6
• Molecular Formula: C25H22O10
• Molecular Weight: 482.44
• Purity: ≥95%
• Synonyms: Silibinin A;Silymarin I
• Target: NF-κB
• Solubility: DMSO: ≥ 31 mg/mL
• Storage: store at -20℃
• IUPAC Name: (2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one
• InChI: 1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20-,23+,24-,25-/m1/s1
• InChIKey: SEBFKMXJBCUCAI-HKTJVKLFSA-N
• SMILES: COC1=C(C=CC(=C1)[C@@H]2[C@H](OC3=C(O2)C=C(C=C3)[C@@H]4[C@H](C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O

Silibinin (CAT: I002745) is a natural flavonoid compound derived from milk thistle seeds (Silybum marianum). It exhibits hepatoprotective effects and is commonly used as a dietary supplement. Silibinin has antioxidant, anti-inflammatory, and anti-fibrotic activities, making it useful for protecting the liver against damage from toxins, drugs, and alcohol. It also shows potential as an anticancer agent, inhibiting tumor growth and inducing cancer cell apoptosis. Silibinin has been investigated for its therapeutic applications in liver disorders, cancer, diabetes, neurodegenerative diseases, and skin disorders.