For research use only. Not for therapeutic Use.
Simufilam (PTI-125) Dihydrochloride is a small molecule modulator that preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.
| Catalog Number | I047464 |
| CAS Number | 2480226-06-8 |
| Molecular Formula | C15H23Cl2N3O |
| Purity | ≥95% |
| Storage | 3 years -20°C powder |
| SMILES | Cl.Cl.CN1CCC2(CC1)NCC(=O)N2CC3=CC=CC=C3 |
| Reference | [1] Hoau-Yan Wang, et al. Neurobiol Aging. 2017 Jul;55:99-114. |
