Simvastatin

• CAT Number: A000513
• CAS Number: 79902-63-9
• Molecular Formula: C₂₅H₃₈O₅
• Molecular Weight: 418.57
• Purity: ≥95%
• Synonyms: 79902-63-9; Zocor; Synvinolin; MK-733; Simvastatine
• Target: HMG-CoA Reductase
• Solubility: >18.3mg/mL in DMSO
• Storage: -20°C
• IUPAC Name: [(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate
• InChI: InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
• InChIKey: RYMZZMVNJRMUDD-HGQWONQESA-N
• SMILES: CCC(C)(C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C

Simvastatin（Cat No.:A000513）is a lipid-lowering medication from the statin class, widely prescribed to manage high cholesterol and reduce cardiovascular disease risk. It works by inhibiting HMG-CoA reductase, a key enzyme in the liver responsible for cholesterol synthesis, effectively lowering low-density lipoprotein (LDL) and triglycerides while modestly increasing high-density lipoprotein (HDL). Simvastatin is used in the prevention of heart attacks, strokes, and related complications in individuals with high cholesterol or at risk of cardiovascular disease. Known for its efficacy and safety, Simvastatin remains a cornerstone in cardiovascular health management.

Reference

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