For research use only. Not for therapeutic Use.
SIRT7 inhibitor 97491 (Cat No.:I015265) is a small molecule compound that selectively inhibits the activity of the Sirtuin 7 (SIRT7) enzyme. SIRT7 is a member of the Sirtuin family of NAD+-dependent deacetylases, which play critical roles in various cellular processes, including gene expression regulation, metabolism, and stress response. By specifically targeting SIRT7, inhibitor 97491 has the potential to modulate SIRT7-mediated functions and pathways. Further research is ongoing to elucidate the precise pharmacological activity and therapeutic applications of this inhibitor, as well as to uncover its molecular interactions and effects on cellular processes regulated by SIRT7.
| Catalog Number | I015265 |
| CAS Number | 1807758-81-1 |
| Molecular Formula | C₁₅H₁₂ClN₃O |
| Purity | ≥95% |
| IUPAC Name | 3-N-[5-(4-chlorophenyl)-1,3-oxazol-2-yl]benzene-1,3-diamine |
| InChI | InChI=1S/C15H12ClN3O/c16-11-6-4-10(5-7-11)14-9-18-15(20-14)19-13-3-1-2-12(17)8-13/h1-9H,17H2,(H,18,19) |
| InChIKey | RMRVZWMKRCLSFX-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC(=C1)NC2=NC=C(O2)C3=CC=C(C=C3)Cl)N |
| Reference | [1]. Ji-Hye Kim, et al. Identification of a Novel SIRT7 Inhibitor as Anticancer Drug Candidate. Biochem Biophys Res Commun. 2019 Jan 8;508(2):451-457. |
