Sirtuin-1 inhibitor 1

• CAT Number: I040544
• CAS Number: 945114-10-3
• Molecular Formula: C20H17N3O2
• Molecular Weight: 331.37
• Purity: ≥95%
• Synonyms: N-[4-(phenylcarbamoylamino)phenyl]benzamide
• InChI: InChI=1S/C20H17N3O2/c24-19(15-7-3-1-4-8-15)21-17-11-13-18(14-12-17)23-20(25)22-16-9-5-2-6-10-16/h1-14H,(H,21,24)(H2,22,23,25)
• InChIKey: OEASWMAWUWRMHZ-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)NC(=O)NC3=CC=CC=C3

Sirtuin-1 inhibitor 1 (Compound 8) is an inhibitor of Sirtuin-1 that plays important roles in obesity-induced diabetes and aging-related diseases[1].

Reference

[1]. Anastasiia Gryniukova, et al. AI-Powered Virtual Screening of Large Compound Libraries Leads to the Discovery of Novel Inhibitors of Sirtuin-1. J Med Chem. 2023 Aug 10;66(15):10241-10251.
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