For research use only. Not for therapeutic Use.
Sisapronil is a non-steroidal anti-inflammatory drug (NSAID) that was explored for its potential analgesic and anti-inflammatory effects. It works by inhibiting the cyclooxygenase (COX) enzymes, particularly COX-2, which play a key role in the inflammatory response and pain signaling pathways. Although sisapronil showed promise in reducing inflammation and providing pain relief, it was not widely adopted in clinical practice. Research on sisapronil contributed to the understanding of COX-2 inhibitors and their role in managing pain and inflammation.
| Catalog Number | I009358 |
| CAS Number | 856225-89-3 |
| Synonyms | Sisapronil; PF-0241851; PF 0241851; PF0241851.; |
| Molecular Formula | C15H6Cl2F8N4 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4 °C for short term, or -20 °C for long term |
| IUPAC Name | 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[2,2-difluoro-1-(trifluoromethyl)cyclopropyl]pyrazole-3-carbonitrile |
| InChI | InChI=1S/C15H6Cl2F8N4/c16-6-1-5(14(20,21)22)2-7(17)10(6)29-11(27)9(8(3-26)28-29)12(15(23,24)25)4-13(12,18)19/h1-2H,4,27H2 |
| InChIKey | VBAVKJPWXSLDSG-UHFFFAOYSA-N |
| SMILES | C1C(C1(F)F)(C2=C(N(N=C2C#N)C3=C(C=C(C=C3Cl)C(F)(F)F)Cl)N)C(F)(F)F |
