For research use only. Not for therapeutic Use.
Sisomicin(CAT: R007647) is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. It exerts its antibacterial effects by binding to the 30S ribosomal subunit, leading to misreading of mRNA and inhibition of bacterial protein synthesis. Sisomicin is structurally related to gentamicin and exhibits potent activity against Gram-negative bacteria and some Gram-positive organisms, including strains resistant to other aminoglycosides. It is particularly effective in treating serious infections such as septicemia, respiratory tract infections, and urinary tract infections. Due to its strong antibacterial properties and resistance to certain modifying enzymes, Sisomicin is also valuable in antibiotic research and drug development.
| CAS Number | 32385-11-8 |
| Synonyms | (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol |
| Molecular Formula | C19H37N5O7 |
| Purity | ≥95% |
| IUPAC Name | (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol |
| InChI | InChI=1S/C19H37N5O7/c1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17/h3,9-18,24-27H,4-7,20-23H2,1-2H3/t9-,10+,11-,12+,13-,14-,15+,16-,17-,18-,19+/m1/s1 |
| InChIKey | URWAJWIAIPFPJE-YFMIWBNJSA-N |
| SMILES | C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC=C(O3)CN)N)N)N)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
