Sisomicin sulfate

• CAT Number: I003945
• CAS Number: 53179-09-2
• Molecular Formula: C19H37N5O7 •2.5 H2SO4
• Molecular Weight: 692.72
• Purity: ≥95%
• Solubility: H2O: ＞ 38 mg/mL
• Storage: Store at -20°C
• IUPAC Name: (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid
• InChI: InChI=1S/2C19H37N5O7.5H2O4S/c2*1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;5*1-5(2,3)4/h2*3,9-18,24-27H,4-7,20-23H2,1-2H3;5*
• InChIKey: CIKNYWFPGZCHDL-ZHFUJENKSA-N
• SMILES: C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC=C(O3)CN)N)N)N)O.C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC=C(O3)CN)N)N)N)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O

Sisomicin Sulfate（Cat No.:I003945）is an aminoglycoside antibiotic closely related to gentamicin, effective against various Gram-negative and some Gram-positive bacteria. It works by binding to the 30S ribosomal subunit, disrupting protein synthesis and leading to bacterial cell death. Sisomicin is particularly useful in treating severe infections like sepsis, urinary tract infections, and respiratory infections. Its broad-spectrum activity makes it a valuable option for hospital-acquired infections caused by resistant pathogens. However, like other aminoglycosides, it requires careful dosing due to potential nephrotoxicity and ototoxicity with prolonged use.