Sitagliptin fenilalanil

• CAT Number: I043364
• CAS Number: 1339955-03-1
• Molecular Formula: C25H24F6N6O2
• Molecular Weight: 554.49
• Purity: ≥95%
• Synonyms: (2S)-2-amino-N-[(2R)-4-oxo-4-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]-3-phenylpropanamide
• InChI: InChI=1S/C25H24F6N6O2/c26-17-12-19(28)18(27)10-15(17)9-16(33-23(39)20(32)8-14-4-2-1-3-5-14)11-22(38)36-6-7-37-21(13-36)34-35-24(37)25(29,30)31/h1-5,10,12,16,20H,6-9,11,13,32H2,(H,33,39)/t16-,20+/m1/s1
• InChIKey: FFZDVHCAHYOEPA-UZLBHIALSA-N
• SMILES: C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)NC(=O)[C@H](CC4=CC=CC=C4)N

Sitagliptin phenylalanine (Sitagliptin Fenilalanil) （Cat No.:I043364）is a modified version of sitagliptin, a commonly used DPP-4 (dipeptidyl peptidase-4) inhibitor. Sitagliptin is used to manage type 2 diabetes by increasing insulin secretion and decreasing glucagon levels in response to meals, thus helping to control blood sugar levels. The phenylalanine modification may enhance the pharmacokinetic properties or receptor binding of the compound, potentially improving its effectiveness or stability. This modified version is being investigated for its potential in diabetes treatment, offering an optimized approach to regulating glucose metabolism and improving glycemic control.