For research use only. Not for therapeutic Use.
SJ000063181 is a potent BMP signaling activator with an EC50 ≤1 µM. SJ000063181 can be used as chemical probes to interrogate BMP signaling due to it can penetrate zebrafish embryos[1].
| Catalog Number | I043368 |
| CAS Number | 945189-68-4 |
| Synonyms | N-(3-chloro-4-fluorophenyl)-5-(2-methylpropyl)-1,2-oxazole-3-carboxamide |
| Molecular Formula | C14H14ClFN2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C14H14ClFN2O2/c1-8(2)5-10-7-13(18-20-10)14(19)17-9-3-4-12(16)11(15)6-9/h3-4,6-8H,5H2,1-2H3,(H,17,19) |
| InChIKey | PBZNVOPQXYXTPC-UHFFFAOYSA-N |
| SMILES | CC(C)CC1=CC(=NO1)C(=O)NC2=CC(=C(C=C2)F)Cl |
| Reference | [1]. Jamie R Genthe, et al. Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway. ACS Chem Biol.2019 Jul 19;14(7):1673. |
