SKA 31

• CAT Number: I010803
• CAS Number: 40172-65-4
• Molecular Formula: C11H8N2S
• Molecular Weight: 200.259
• Purity: ≥95%
• Synonyms: Naphtho[1,2-d]thiazol-2-ylamine
• Target: Potassium Channel
• Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
• Storage: Store at +4C
• IUPAC Name: benzo[e][1,3]benzothiazol-2-amine
• InChI: InChI=1S/C11H8N2S/c12-11-13-10-8-4-2-1-3-7(8)5-6-9(10)14-11/h1-6H,(H2,12,13)
• InChIKey: FECQXVPRUCCUIL-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C=CC3=C2N=C(S3)N

SKA 31(CAT: I010803) is a chemical compound that acts as a potent and selective activator of small and intermediate conductance calcium-activated potassium (SK/IK) channels. It enhances the opening of these channels, resulting in the efflux of potassium ions from cells. SK/IK channels are involved in the regulation of neuronal excitability and play a role in various physiological processes, including synaptic transmission and smooth muscle tone. By activating SK/IK channels, SKA 31 has the potential to modulate neuronal activity and contribute to the regulation of cellular functions.