For research use only. Not for therapeutic Use.
SKI2852(Cat No.:I009513)is an investigational small molecule that functions as an inhibitor of specific enzymes involved in the regulation of cellular signaling pathways. It is primarily being researched for its potential applications in cancer therapy, particularly for targeting tumor cells and inhibiting their growth and proliferation. SKI2852 may also have a role in modulating the immune system or affecting other disease-related pathways. As an experimental compound, its safety, pharmacokinetics, and therapeutic efficacy are still under investigation in preclinical or early-stage clinical trials, with further studies required to establish its potential.
Catalog Number | I009513 |
CAS Number | 1346554-47-9 |
Synonyms | SKI2852; SKI-2852; SK I2852.;2‑((R)‑4-(2-Fluoro-4-(methylsulfonyl)phenyl)-2-methylpiperazin-1-yl)‑N‑((1R,2s,3S,5S,7S)‑5-hydroxyadamantan-2-yl)pyrimidine-4-carboxamide |
Molecular Formula | C27H34FN5O4S |
Purity | ≥95% |
Target | 11β-HSD1 inhibitor |
Solubility | Soluble in DMSO |
Storage | 0 - 4 °C for short term, or -20 °C for long term |
IUPAC Name | 2-[(2R)-4-(2-fluoro-4-methylsulfonylphenyl)-2-methylpiperazin-1-yl]-N-[(1S,3R)-5-hydroxy-2-adamantyl]pyrimidine-4-carboxamide |
InChI | InChI=1S/C27H34FN5O4S/c1-16-15-32(23-4-3-20(11-21(23)28)38(2,36)37)7-8-33(16)26-29-6-5-22(30-26)25(34)31-24-18-9-17-10-19(24)14-27(35,12-17)13-18/h3-6,11,16-19,24,35H,7-10,12-15H2,1-2H3,(H,31,34)/t16-,17?,18-,19+,24?,27?/m1/s1 |
InChIKey | SSKKTEYBWOVEET-GMILZOMTSA-N |
SMILES | C[C@@H]1CN(CCN1C2=NC=CC(=N2)C(=O)NC3[C@@H]4CC5C[C@H]3CC(C4)(C5)O)C6=C(C=C(C=C6)S(=O)(=O)C)F |