For research use only. Not for therapeutic Use.
SLU-PP-332 is a pan-Estrogen Receptor/ERR agonist with EC50 values of 98, 230 and 430 nM for ERRα, ERRβ and ERRγ, respectively. SLUPP-332 enhances mitochondrial function and cellular respiration in skeletal muscle cell lines. SLU-PP-332 has the potential to study metabolic diseases as well as improve muscle function[1].
| Catalog Number | I040881 |
| CAS Number | 303760-60-3 |
| Synonyms | 4-hydroxy-N-[(E)-naphthalen-2-ylmethylideneamino]benzamide |
| Molecular Formula | C18H14N2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H14N2O2/c21-17-9-7-15(8-10-17)18(22)20-19-12-13-5-6-14-3-1-2-4-16(14)11-13/h1-12,21H,(H,20,22)/b19-12+ |
| InChIKey | RNZIMBFHRXYRLL-XDHOZWIPSA-N |
| SMILES | C1=CC=C2C=C(C=CC2=C1)C=NNC(=O)C3=CC=C(C=C3)O |
| Reference | [1]. Billon C, et al. Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. ACS Chem Biol. 2023 Apr 21;18(4):756-771. |
