For research use only. Not for therapeutic Use.
SM-102(Cat No.:I036392) is an ionizable amino lipid that is commonly utilized alongside other lipids in the creation of lipid nanoparticles (LNPs). When luciferase mRNA is administered in lipid nanoparticles containing SM-102, it induces luciferase expression in the liver of mice. SM-102-containing formulations have played a vital role in the development of lipid nanoparticles for delivering mRNA-based vaccines. These LNPs offer a promising approach for the effective and targeted delivery of mRNA, thereby facilitating the development of mRNA-based vaccine candidates.
Catalog Number | I036392 |
CAS Number | 2089251-47-6 |
Synonyms | SM-102; SM102; SM 102; |
Molecular Formula | C44H87NO5 |
Purity | 98% |
Target | Liposome |
Solubility | To be determined |
Appearance | Oily liquid |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | heptadecan-9-yl 8-((2-hydroxyethyl)(6-oxo-6-(undecyloxy)hexyl)amino)octanoate |
InChI | InChI=1S/C44H87NO5/c1-4-7-10-13-16-17-18-24-32-41-49-43(47)35-29-25-31-38-45(39-40-46)37-30-23-19-22-28-36-44(48)50-42(33-26-20-14-11-8-5-2)34-27-21-15-12-9-6-3/h42,46H,4-41H2,1-3H3 |
InChIKey | BGNVBNJYBVCBJH-UHFFFAOYSA-N |
SMILES | OCCN(CCCCCC(OCCCCCCCCCCC)=O)CCCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O |