For research use only. Not for therapeutic Use.
SM19712 (Cat.No:I036399) is a nonpeptide endothelin converting enzyme inhibitor.
| Catalog Number | I036399 |
| CAS Number | 194542-56-8 |
| Synonyms | SM19712; SM-19712; SM 19712. |
| Molecular Formula | C18H13ClN5NaO3S |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | sodium ((4-chlorophenyl)sulfonyl)((4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl)carbamoyl)amide |
| InChI | InChI=1S/C18H14ClN5O3S.Na/c1-12-16(11-20)17(24(22-12)14-5-3-2-4-6-14)21-18(25)23-28(26,27)15-9-7-13(19)8-10-15;/h2-10H,1H3,(H2,21,22,23,25);/q;+1/p-1 |
| InChIKey | FBSZSOXTWRKLKD-UHFFFAOYSA-M |
| SMILES | O=S(C1=CC=C(Cl)C=C1)([N-]C(NC2=C(C#N)C(C)=NN2C3=CC=CC=C3)=O)=O.[Na+] |
| Reference | 1: Hasdemir B, Mahajan S, Bunnett NW, Liao M, Bhargava A. Endothelin-converting enzyme-1 actions determine differential trafficking and signaling of corticotropin-releasing factor receptor 1 at high agonist concentrations. Mol Endocrinol. 2012 Apr;26(4):681-95. doi: 10.1210/me.2011-1361. Epub 2012 Feb 9. PubMed PMID: 22322595; PubMed Central PMCID: PMC3327357. |
