For research use only. Not for therapeutic Use.
Sm4 is a SOX18 inhibitor. Sm4 shows SOX18-DNA binding inhibitory activity. Sm4 selectively affects SOX18 transcriptional output in vitro. Sm4 blocks SoxF transcriptional activity in vivo. Sm4 can be used for cancer metastasis and vascular cancers research[1].
| Catalog Number | M011079 |
| CAS Number | 365542-77-4 |
| Synonyms | 2-hydroxy-6-(2-naphthalen-2-ylethyl)benzoic acid |
| Molecular Formula | C19H16O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C19H16O3/c20-17-7-3-6-15(18(17)19(21)22)11-9-13-8-10-14-4-1-2-5-16(14)12-13/h1-8,10,12,20H,9,11H2,(H,21,22) |
| InChIKey | GGVFBUYNEPBFQT-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C=C(C=CC2=C1)CCC3=C(C(=CC=C3)O)C(=O)O |
| Reference | [1]. Mathias FRANCOIS. Inhibitors of sox18 protein activity for treating angiogenesis- and/or lymphangiogenesis-related diseases. Patent, WO2018112545A1. |
