SMT-738

• CAT Number: I040133
• Molecular Formula: C21H24N6O2
• Molecular Weight: 392.45
• Purity: ≥95%
• Synonyms: 2-amino-1-[6-[2-amino-5-(3-methylpyridin-4-yl)-1H-imidazol-4-yl]-2,3-dihydro-1,4-benzoxazin-4-yl]-2-methylpropan-1-one
• InChI: InChI=1S/C21H24N6O2/c1-12-11-24-7-6-14(12)18-17(25-20(22)26-18)13-4-5-16-15(10-13)27(8-9-29-16)19(28)21(2,3)23/h4-7,10-11H,8-9,23H2,1-3H3,(H3,22,25,26)
• InChIKey: JPOVQSBUKRMDME-UHFFFAOYSA-N
• SMILES: CC1=C(C=CN=C1)C2=C(N=C(N2)N)C3=CC4=C(C=C3)OCCN4C(=O)C(C)(C)N

SMT-738 (Cat No.: I040133) is a small-molecule inhibitor designed to target specific enzymes or pathways involved in cellular processes like cell growth, apoptosis, or DNA repair. Although detailed mechanisms may vary depending on the context, SMT-738 has been studied for its potential in cancer research, where it could modulate tumor cell survival or enhance the effects of other therapies. Its selectivity makes it a promising candidate for targeted treatment strategies, potentially offering benefits in treating cancers resistant to conventional therapies.

Reference

[1]. E B M Breidenstein, et al. SMT-738: a novel small-molecule inhibitor of bacterial lipoprotein transport targeting Enterobacteriaceae. Antimicrob Agents Chemother. 2024 Jan 10;68(1):e0069523.
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