SMTIN-T140

• CAT Number: I043608
• CAS Number: 2851532-40-4
• Molecular Formula: C36H34BrClFN5OP+
• Molecular Weight: 718.02
• Purity: ≥95%
• Synonyms: 6-[2-amino-9-[(4-bromo-2-fluorophenyl)methyl]-6-chloro-8-oxopurin-7-yl]hexyl-triphenylphosphanium
• InChI: InChI=1S/C36H34BrClFN5OP/c37-27-21-20-26(31(39)24-27)25-44-34-32(33(38)41-35(40)42-34)43(36(44)45)22-12-1-2-13-23-46(28-14-6-3-7-15-28,29-16-8-4-9-17-29)30-18-10-5-11-19-30/h3-11,14-21,24H,1-2,12-13,22-23,25H2,(H2,40,41,42)/q+1
• InChIKey: WMHQIAATFFUMMC-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)[P+](CCCCCCN2C3=C(N=C(N=C3Cl)N)N(C2=O)CC4=C(C=C(C=C4)Br)F)(C5=CC=CC=C5)C6=CC=CC=C6

SMTIN-T140（Cat No.:I043608）is a synthetic peptide designed to specifically inhibit the binding of chemokine receptors, particularly CXCR4, which is involved in cell migration, immune response, and cancer metastasis. CXCR4 is overexpressed in various cancers and plays a crucial role in tumor progression and the spread of cancer cells. By blocking the interaction between CXCR4 and its ligand, SMTIN-T140 aims to inhibit cancer cell migration and metastasis. This peptide is being studied for its potential as a therapeutic agent in treating cancers, especially those where CXCR4 is a major driver of tumor dissemination.