SN-38-d3

• CAT Number: S000012
• CAS Number: 718612-49-8
• Molecular Formula: C22H17D3N2O5
• Molecular Weight: 395.42
• Purity: ≥95%
• Target: Antibody-drug Conjugate/ADC Related
• IUPAC Name: (19S)-19-ethyl-7,19-dihydroxy-10-(2,2,2-trideuterioethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
• InChI: InChI=1S/C22H20N2O5/c1-3-12-13-7-11(25)5-6-17(13)23-19-14(12)9-24-18(19)8-16-15(20(24)26)10-29-21(27)22(16,28)4-2/h5-8,25,28H,3-4,9-10H2,1-2H3/t22-/m0/s1/i1D3
• InChIKey: FJHBVJOVLFPMQE-MVTYLIICSA-N
• SMILES: [2H]C([2H])([2H])CC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)O

SN-38-d3 is a high-purity deuterated compound used in advanced pharmaceutical research. This isotopically labeled version of SN-38, the active metabolite of the anticancer drug irinotecan, is essential for studies involving topoisomerase I inhibitors, cancer therapeutics, pharmacokinetics, and metabolic pathways. Featuring three deuterium atoms, it ensures precise and reliable analytical results. Its advanced formulation provides enhanced stability and consistency, making it suitable for various experimental setups. Ideal for oncology research and drug development, SN-38-d3 integrates seamlessly into existing protocols, offering a robust and cost-effective solution for high-precision scientific investigations.