Snf 8815

• CAT Number: I036446
• CAS Number: 154336-13-7
• Molecular Formula: C56H68N10O13
• Molecular Weight: 1089.21
• Purity: 98%
• Synonyms: Snf 8815; Snf-8815; Snf8815; 28-Mephe-31-N-meile-cck (26-33)
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (3S,6S,9S,15R,18S,21S)-9-((1H-indol-3-yl)methyl)-21-amino-3-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-6-butyl-18-(4-hydroxybenzyl)-7-methyl-5,8,11,14,17,20-hexaoxo-15-((R)-1-phenylethyl)-4,7,10,13,16,19-hexaazatricosanedioic acid
• InChI: 1S/C56H68N10O13/c1-4-5-20-45(54(77)64-43(29-48(71)72)52(75)62-41(50(58)73)25-33-14-8-6-9-15-33)66(3)56(79)44(27-36-30-59-40-19-13-12-18-38(36)40)61-46(68)31-60-55(78)49(32(2)35-16-10-7-11-17-35)65-53(76)42(26-34-21-23-37(67)24-22-34)63-51(74)39(57)28-47(69)70/h6-19,21-24,30,32,39,41-45,49,59,67H,4-5,20,25-29,31,57H2,1-3H3,(H2,58,73)(H,60,78)(H,61,68)(H,62,75)(H,63,74)(H,64,77)(H,65,76)(H,69,70)(H,71,72)/t32-,39+,41+,42+,43+,44+,45+,49-/m1/s1
• InChIKey: VEJMMYDVUKVYEP-HYXUPHFQSA-N
• SMILES: N[C@H](C(N[C@@H](Cc1ccc(O)cc1)C(N[C@H]([C@H](C)c2ccccc2)C(NCC(N[C@@H](Cc3c4ccccc4[nH]c3)C(N(C)[C@@H](CCCC)C(N[C@@H](CC(O)=O)C(N[C@@H](Cc5ccccc5)C(N)=O)=O)=O)=O)=O)=O)=O)=O)CC(O)=O

Snf 8815 is a cholecystokinin-B (CCK-B) agonist.

Reference

1: Povoski SP, Zhou W, Longnecker DS, Jensen RT, Mantey SA, Bell RH Jr. Stimulation of in vivo pancreatic growth in the rat is mediated specifically by way of cholecystokinin-A receptors. Gastroenterology. 1994 Oct;107(4):1135-46. Review. PubMed PMID: 7523219.
2: Povoski SP, Zhou W, Longnecker DS, Roebuck BD, Bell RH Jr. Growth of azaserine-induced putative preneoplastic nodules in the rat pancreas is mediated specifically by way of cholecystokinin-A receptors. Ann N Y Acad Sci. 1994 Mar 23;713:439-41. PubMed PMID: 8018216.
3: Povoski SP, Zhou W, Longnecker DS, Roebuck BD, Bell RH Jr. Stimulation of growth of azaserine-induced putative preneoplastic lesions in rat pancreas is mediated specifically by way of cholecystokinin-A receptors. Cancer Res. 1993 Sep 1;53(17):3925-9. PubMed PMID: 8358719.