SNX0723

For research use only, not for therapeutic use.

  • CAT Number: I036458
  • CAS Number: 1073969-18-2
  • Molecular Formula: C22H26FN3O3
  • Molecular Weight: 399.47
  • Purity: 98%
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SNX0723(Cat No.:I036458)is a selective inhibitor of the protein kinase CK2, which is implicated in various cellular processes, including cell growth, proliferation, and survival. By targeting CK2, SNX0723 disrupts its enzymatic activity, leading to altered signaling pathways that can promote apoptosis in cancer cells. This compound has shown promise in preclinical studies for its potential efficacy against a range of malignancies, including those resistant to conventional therapies. Ongoing research aims to evaluate its therapeutic applications and safety profile, positioning SNX0723 as a potential candidate for targeted cancer treatments in future clinical settings.


Catalog Number I036458
CAS Number 1073969-18-2
Synonyms

SNX0723; SNX 0723; SNX- 0723.

Molecular Formula C22H26FN3O3
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name 2-fluoro-6-[[(3S)-oxolan-3-yl]amino]-4-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)benzamide
InChI InChI=1S/C22H26FN3O3/c1-12-10-26(17-8-22(2,3)9-18(27)19(12)17)14-6-15(23)20(21(24)28)16(7-14)25-13-4-5-29-11-13/h6-7,10,13,25H,4-5,8-9,11H2,1-3H3,(H2,24,28)/t13-/m0/s1
InChIKey GAGDTKJJVCLACJ-ZDUSSCGKSA-N
SMILES CC1=CN(C2=C1C(=O)CC(C2)(C)C)C3=CC(=C(C(=C3)F)C(=O)N)N[C@H]4CCOC4
Reference

1. Putcha P, Danzer KM, Kranich LR, Scott A, Silinski M, Mabbett S, Hicks CD, Veal JM, Steed PM, Hyman BT et al.. (2010) Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity. J. Pharmacol. Exp. Ther., 332 (3): 849-57. [PMID:19934398]

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