Sodium 4-pentynoate

For research use only. Not for therapeutic Use.

  • CAT Number: I000137
  • CAS Number: 101917-30-0
  • Molecular Formula: C5H5NaO2
  • Molecular Weight: 120.08
  • Purity: ≥95%
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Sodium 4-pentynoate is a alkynylacetate analogue, can be metabolically incorporated onto cellular proteins through biosynthetic mechanisms for profiling of acetylated proteins in diverse cell types[1]. Sodium 4-pentynoate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Sodium 4-pentynoate (0.01-10 mM; 0.5-8 h) is used to dose- and time-dependent metabolic labeling in Jurkat T cells[1].


Catalog Number I000137
CAS Number 101917-30-0
Synonyms

sodium;pent-4-ynoate

Molecular Formula C5H5NaO2
Purity ≥95%
InChI InChI=1S/C5H6O2.Na/c1-2-3-4-5(6)7;/h1H,3-4H2,(H,6,7);/q;+1/p-1
InChIKey IWIICCMJXWKGSG-UHFFFAOYSA-M
SMILES C#CCCC(=O)[O-].[Na+]
Reference

[1]. Yang YY, et al. Bioorthogonal chemical reporters for monitoring protein acetylation. J Am Chem Soc. 2010 Mar 24;132(11):3640-1.
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