For research use only. Not for therapeutic Use.
Sodium 4-pentynoate is a alkynylacetate analogue, can be metabolically incorporated onto cellular proteins through biosynthetic mechanisms for profiling of acetylated proteins in diverse cell types[1]. Sodium 4-pentynoate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Sodium 4-pentynoate (0.01-10 mM; 0.5-8 h) is used to dose- and time-dependent metabolic labeling in Jurkat T cells[1].
Catalog Number | I000137 |
CAS Number | 101917-30-0 |
Synonyms | sodium;pent-4-ynoate |
Molecular Formula | C5H5NaO2 |
Purity | ≥95% |
InChI | InChI=1S/C5H6O2.Na/c1-2-3-4-5(6)7;/h1H,3-4H2,(H,6,7);/q;+1/p-1 |
InChIKey | IWIICCMJXWKGSG-UHFFFAOYSA-M |
SMILES | C#CCCC(=O)[O-].[Na+] |
Reference | [1]. Yang YY, et al. Bioorthogonal chemical reporters for monitoring protein acetylation. J Am Chem Soc. 2010 Mar 24;132(11):3640-1. |